Pascal Ferré

Les travaux de Pascal Ferré et de ses collaborateurs ont donné lieu à la publication de près de 160 articles originaux dans des revues scientifiques internationales et 80 revues ou chapitres d'ouvrages.

Sélection des principales publications

• Ferré P, Pégorier JP, Girard J. The effect of inhibition of gluconeogenesis in suckling newborn rats. Biochem J 162: 209-212, 1977
• Ferré P, Pégorier JP, Williamson DH, Girard J. Interactions in vivo between oxidation of non-esterified fatty acids and gluconeogenesis in the newborn rat. Biochem J 82: 593-598, 1979
• Ferré P, Leturque A, Burnol AF, Pénicaud L, Girard J. A method to quantify glucose utilization in vivo in skeletal muscle and white adipose tissue of the anesthetized rat. Biochem J 228 : 103-110, 1985.
• Bougneres .F, Lemmel C, Ferré P, Bier DM. Ketone body transport in the human neonate and infant. J Clin Invest 77: 42-48, 1986
• Bougneres PF,Ferré P. Study of ketone body kinetics in children by a combined perfusion of 13C and 2H3 tracers. Am J. Physiol 253: E496-E502, 1987.
• Foufelle F, Gouhot B, Pegorier JP, Perdereau D, Girard J, Ferré P. Glucose stimulation of lipogenic enzyme gene expression in cultured white adipose tissue : a role for glucose-6-phosphate. J Biol Chem 267: 20543-546, 1992.
• Hallakou S, Doare L, Foufelle F, Kergoat M, Guerre-Millo M, Dugail I, Morin J, Auwerx J, Ferré P. Pioglitazone induces the differentiation of adipocytes in the obese Zucker fa/fa rat. Diabetes 46: 1393-99, 1997
• Foretz M, Carling D, Guichard G, Ferré P, Foufelle F. AMP-activated protein kinase inhibits the glucose-activated expression of Fatty Acid Synthase gene in rat hepatocytes. J Biol Chem 273: 14767-771, 1998.
• Foretz M, Guichard C, Ferré P, Foufelle F. Sterol Regulatory Element Binding Protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes. Proc Natl Acad Sci USA 96: 12737-742, 1999.
• Woods A, Azzout-Marniche D, Foretz M, Stein SC, Lemarchand P, Foufelle F, Ferré P, Carling D. Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase. Mo. Cell Biol 20: 6704-711, 2000.
• Becard D, Hainault I, Azzout-Marniche D, Bertry-Coussot L, Ferré P, Foufelle F. Adenovirus-mediated overexpression of Sterol Regulatory Element Binding Protein 1-c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice. Diabetes 50: 2425-30, 2001.
• Minokoshi Y, Alquier T, Furukawa N, Kim YB, Lee A, Xue B, Mu J, Foufelle F, Ferré P, Birnbaum MJ, Stuck B, Kahn BB. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in hypothalamus. Nature 428: 569-74, 2004.
• Foretz M, Pacot I. Dugail P. Lemarchand C, Guichard X. Le Lièpvre C, Berthelier-Lubrano B. Spiegelman JB, Kim, Ferré P, Foufelle F. ADD1/SREBP1c is required in the activation of hepatic lipogenic gene expression by glucose. Mol Cell Biol 19: 3760-68, 1999.
• Daval M, Diot-Dupuy F, Bazin R, Hainault I, Viollet B, Vaulont S, Hajduch E, Ferré P, Foufelle F. Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes. J Biol Chem 280: 25250-257, 2005.
• Hegarty BD, Bobard A, Hainault I, Ferré P, Bossard P, Foufelle F. Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c. Proc Natl Acad Sci USA 102: 791-96, 2005.
• Sobngwi E, Choukem SP, Agbalika F, Blondeau B, Fetita LS, Lebbe C, Thiam D, Cattan P, Larghero J, Foufelle F, Ferré P, Vexiau P, Calvo F, Gautier JF. Ketosis-prone type 2 diabetes mellitus and human herpesvirus 8 infection in sub-saharan africans. JAMA 299: 2770-76, 2008.
• Kammoun HL, Chabanon H, Hainault I, Luquet S, Magnan C, Koike T, Ferré P, Foufelle F. GRP78 inhibits SREBP-1c cleavage induced by insulin and endoplasmic reticulum stress: consequences for hepatic steatosis. J Clin Invest 119(5): 1201-15, 2009.
• Issad T, Penicaud L, Ferré P, Kande J, Baudon MA, Girard J. Effects of fasting on tissue glucose utilization in conscious resting rats: major glucose sparing effect in working muscles. Biochem J 246: 241-44, 1987.
• Dentin R, Tomas-Cobos L, Foufelle F, Leopold J, Girard J, Postic C, Ferré P. Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver. J Hepatol 56(1): 199-209, 2012.

Revues

• Girard J, Ferré P, Pégorier JP, Duée PH. Adaptation of glucose and lipid metabolism during the suckling period and the suckling-weaning transition. Physiol Rev 72: 507-62, 199
• Girard J, Ferré P, Foufelle F. Mechanisms by which carbohydrates regulate glycolytic and lipogenic enzyme gene expression. Ann Rev Nutr 17: 325-352, 1997.
• Foufelle F, Ferré P. New Perspectives in the Regulation of Hepatic Glycolytic and Lipogenic Genes by Glucose and Insulin. Biochem J, 66: 377-391, 2002.
• Ferré P. The Biology of PPARs. Relationship with lipid metabolism and insulin sensitivity. Diabetes 53 Suppl 1: S43-50, 2004.
• Daval M, Foufelle F, Ferré P. Functions of AMP-activated protein kinase in adipose tissue. J Physiol 574: 55-62, 2006.
• Ferré P, Foufelle F. Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c. Diabetes Obes Metab 12 Suppl 2: 83-92, 2010.
• Flamment M, Hajduch E, Ferré P, Foufelle F. New insights into ER stress-induced insulin resistance. Trends Endocrinol Metab 23(8): 381-90, 2012.